• 专利附录
  • 专利说明
  • 权利要求
  • 类似技术
  • 同族专利
  • 引用文献
  • 法律状态
  • 优先权
    • 专利摘要:
    The invention relates to devices for distributing fluid samples, such as blood samples, from a test tube to a variety of other tubes, so that various types of analysis can be performed on divided portions of the test liquid, and it allows to increase the reliability of the device and simplify it. A device for automatically distributing samples of liquid contains sample and sample dispensing means having tip 3, air cylinder 15 with a piston connected to tip 3 by an air tube 7, unit for determining the position of tip 3 in tube 6 and means for moving tip 3 relative to tubes 6. The unit for determining the position of the tip 3 contains an air supply source 12 and a pressure sensor 16 connected to it by an air tube 11. The device also has a multi-way valve 8, the first inlet 10 of which is connected air cylinder 15, and its output is connected to the tip 3 and a means for switching valve 8 is electrically connected to the pressure sensor 16, the pressure sensor 16 is coupled to the second input 9 of the valve. 3 il.
    公开号:SU1671149A3
    申请号:SU884355721
    申请日:1988-04-29
    公开日:1991-08-15
    发明作者:Итох Теруаки
    申请人:ТеруакиИтох(иР)；
    IPC主号:
    专利说明:

    The invention relates to devices for distributing fluid samples, such as blood samples, from a test tube to a plurality of other tubes, so that various types of analysis can then be performed on divided portions of the test fluid.
    The aim of the invention is to increase the reliability and simplify the device.
    FIG. 1 shows the device in front; general form; in fig. 2 - the same, side view; in fig. 3 is a diagram of a sample distribution unit.
    The device comprises a casing 1, a movable base 2 mounted on the casing 1, a sample distribution compartment attached to the base 2 and containing five distribution tips 3, an L-shaped stand 4 having a vertical portion extending upwards from the casing 1, and a horizontal part extending from the vertical part; a control panel 5 attached to the free end of the L-shaped stand 4. Case 1 comprises a control system including a sequencing device. The base 2 can be moved along the arrow X, as well as in the direction of the arrow Y, as shown in FIG. 1 and 2.
    The device also contains a sample distribution compartment having five identical distribution units. The blood sample is in a common test tube 6, the serum being separated from the cells using a release agent. Each tip 3 can be moved up and down using a drive mechanism (not shown), so that its remote end can be inserted into a common tube 6. The proximal end of tip 3 is connected to one end of the air tube 7 tightly. The other end of the tube 7 is connected to a multi-way valve 8 having two inlets 9 and 10 for air. The first inlet 9 is connected by a tube 11c with an air supply source containing a source 12 of compressed air and a pressure regulator 13. The second inlet 10 is connected via a tube 14 to an air cylinder 15 having a piston. Pressure sensor 16 is connected to tube 11 to determine changes in air pressure through tube 11. When detecting a change in air pressure, sensor 16 produces and sends a signal to multi-way valve 8. In response to this signal, valve 8 connects tube 7 to tube 14 Once the valve 8 connects the tubes 7 and 14, the serum can be sucked from the tube 6 into the tip 3 and remain there when the piston moves in the direction of arrow A, and can flow out of the tip 3 into the predetermined test tube (not shown), when the piston move in a direction of arrow B. Pressure switch 17 is connected with a tube 7 for checking tip 3 on the fault type clogging.
    The device works as follows.
    0Includes air supply 12,
    whereby air is supplied at low speed to tip 3 through pressure sensor 16 and multi-port valve 8. Consequently, air is continuously supplied from
    5 distribution tip 3 through its far end. At the same time, the tip 3 gradually lowers into the common tube 6. At the moment when the far end of the tip 3 reaches the serum, the air flow encounters resistance and the pressure of air going through the tubes 7 and 11 rises. The pressure sensor 16 detects this increase in pressure and produces signal supplied to the multi-way valve 8. In response to this
    5, the signal valve 8 disconnects the tube 7 from the first inlet 9 and connects the tube 7 to the second inlet 10, thereby connecting the tube 7 to the tube 14. Then the piston of the air cylinder 15 moves in the direction of the arrow A. As a result, the serum is sucked into the distribution tip 3. At the same time, pressure switch 17 determines whether tip 3 is clogged or not. When certain
    5, the amount of serum is introduced into the tip 3, the piston stops and this amount of serum remains in the tip 3.
    The amount of serum contained in
    The total tube 6 is calculated based on the level of the surface of the separating agent, the level of the surface of the serum and the internal diameter of the tube 6. The distributor tip 3 is lowered in accordance with the calculated amount of serum so that the distal end of the separator 3 can be prevented from touching.
    Thereafter, the movable base 2 is moved to the direction of the place where the specified test tubes are located until the distribution tips 3 are installed directly above the specified test tubes.
    5 accordingly. Each tip 3 is then lowered until its far end is in the predetermined tube. The piston of the air cylinder 15 moves in the direction of the arrow B, whereby the serum is fed from the tip 3 to the predetermined tube. Thus, the serum is discharged from the total tube 6 into a predetermined tube. After that, the tip 3 is replaced with a new one, so that the test liquid is given out from the common test tube to the specified test tube. Serum may be dispensed from tip 3 to a plurality of test tubes. In the proposed device, each distribution tip 3 is installed in a test tube at such a level that a liquid sample can be fed into the tip from the test tube without the aid of a complex sensor (e.g. photo sensor) to determine the surface level of the liquid in the tube or a complex control device to move the tip to a predetermined level according to the output of the sensor representing the level of the surface of the liquid & gi. The absence of complex nodes, in turn, provides an increase on the.
    权利要求:
    Claims (1)
    [1]
    reliability of the proposed device;) Formula of the Invention A device for automatically producing liquid samples, including a sample pickup and dispensing device having a tip, an air cylinder with a piston connected to the tip of an air tube, a device for determining the position of the tip in a test tube and means for moving the tip relative to tubes, characterized in that. in order to increase the reliability and simplify the device, the tip positioning unit contains a supply source
    5 air and a pressure sensor connected to it by an air tube, the device is equipped with a multi-way valve, the first inlet of which is connected to the air cylinder, and the outlet with the tip and means
    0 for switching a valve electrically connected to a pressure sensor, the pressure sensor being connected to the second valve inlet.
    V
    T / G7T
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    同族专利:
    公开号 | 公开日
    JPS63175864U|1988-11-15|
    引用文献:
    公开号 | 申请日 | 公开日 | 申请人 | 专利标题
    JPS5741163B2|1977-06-22|1982-09-01|
    JPH0121467B2|1980-05-23|1989-04-21|Aloka|JP2926983B2|1990-11-29|1999-07-28|株式会社島津製作所|Pipette equipment|
    JP2775618B2|1993-03-18|1998-07-16|株式会社堀場製作所|Sample liquid dispensing / dispensing device and sample liquid dispensing / dispensing method using the device|
    JP2693356B2|1993-06-03|1997-12-24|アロカ株式会社|Dispensing device|
    JP2688163B2|1993-06-04|1997-12-08|アロカ株式会社|Dispensing device|
    DE10022398B4|2000-04-28|2011-03-17|Eppendorf Ag|Gas cushion micro-dosing system|
    法律状态:
    优先权:
    申请号 | 申请日 | 专利标题
    JP6702387U|JPS63175864U|1987-05-02|1987-05-02|
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